About H1N1 vaccine, H1N1vaccine production, H1N1 vaccine manufacturers

by AJC1

Question by Kay: How can a vaccine bring the development of immunity?
Have a bio 20 test and cant seem to find the answer anywhere, any help would be appreciated!

Best answer:

Answer by H
When you are injected with a vaccine (usually dead or weakened live viruses or bacteria), a type of immune cell called an antigen-presenting cell (APC) or macrophage picks them up, “eats” them, and displays bits of the bugs on its cell surface as a signal. Then it goes off to the lymph nodes where your B and T cells hang out. These are the major players of your “adaptive” immune system, which needs to be activated before it can work. The APC presents the bug pieces to the B cells, which then activate and differentiate into plasma cells and memory cells. The plasma cells make antibodies so you can fight the infection (which is why you sometimes have mild fever, swelling etc after vaccination). The memory cells remember the type of bug that was presented; if you ever get infected with it in the future, the memory cells recognize the bug and activate the immune system response quickly so you can fight it off.

So summary: the bacteria/virus in the vaccine gets picked up by APCs and presented to B cells in the lymph node. The B cells then become plasma cells and memory cells, and the memory cells “memorise” the bacteria/virus so it can attack it with full force if you get infected with it for real.

That was long, but hope that helped.

Know better? Leave your own answer in the comments!

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