Treating women with early stage breast cancer with a combination of chemotherapy and the molecularly targeted drug Herceptin significantly increases survival in patients with a specific genetic mutation that results in very aggressive disease, a researcher with UCLA’s Jonsson Comprehensive Cancer Center reports. Read more…
A large study of the daughters of women who had been given DES, the first synthetic form of estrogen, during pregnancy has found that exposure to the drug while in the womb (in utero) is associated with many reproductive problems and an increased risk of certain cancers and pre-cancerous conditions. Read more…
A possible new target for breast cancer therapy comes from the discovery that the Tyk2 protein helps suppress the growth and metastasis of breast tumors, as reported in Journal of Interferon & Cytokine Research, a peer-reviewed journal published by Mary Ann Liebert, Inc. Read more…
Over the next decade, the population of cancer survivors over 65 years of age will increase by approximately 42 percent. Read more…
In cancer, genes turn on and off at the incorrect times, proteins aren’t folded properly, and cellular growth and proliferation get out of control. Even a cancer cell’s metabolism goes haywire, as it loses the ability to appropriately sense nutrients and use them to generate energy. One particular piece of cellular machinery that is known to malfunction in a number of cancers is a group of proteins called mTORC1. This master control center coordinates many cellular functions by sensing external signals such as nutrients and growth factors and telling cells how to respond. Read more…
Medical researchers are demonstrating that Office of Naval Research (ONR)-funded software developed for finding and recognizing undersea mines can help doctors identify and classify cancer-related cells. Read more…
A new study finds liver cancer incidence rates continue to increase in some low-risk parts of the world such as North America, and are decreasing in some of the highest risk countries of Asia. Despite this, the incidence rates in Asian countries remain twice as high as those in Africa and more than four times as high as rates in North America. Read more…
A series of novel imaging agents could make it possible to “see” tumors in their earliest stages, before they turn deadly. Read more…
1,630 of people under the age of 50 years ancient were screened. Hence, the results obtained from these younger groups were more prone to uncertainty than larger, older groups. This study tested screening for bowel cancer using colonoscopy; this is not the standard method in all countries. In England, Wales and Northern Ireland, patients over 60 years ancient are invited to be screened using a faecal occult blood (FOB) test kit that can be done at home. Those in Scotland can be screened from the age of 50 years ancient. The FOB tests for blood in the faeces. If blood is detected, an invitation of further investigation into the cause of the bleeding, which may include a colonoscopy, is made. The age and sex differences for screening using the FOB test are not considered in this study and these findings are not as applicable to the UK as they would be to countries with a national colonoscopy screening programme such as Austria and the US. Read more…
The association between average amount of eggs eaten per week and risk of lethal prostate cancer became non-significant when the researchers analysed data collected up to the point of development of a lethal form of the disease (that is, disease progression or death). There was no significant association between the average amount of red meat eaten and the risk of lethal prostate cancer. Men who consumed more red meat or eggs tended to exercise less and have a higher BMI, and were more likely to smoke and have a family history of prostate cancer. Read more…
